I'm running a 32" monitor piggy-backed off an MS Surface Pro 4. As it is used as a TV screen, it is some way away from where I sit, that and poor eyesight means I adjust the W11 "Make Text Size Bigger" option, setting it to 180%. So I can for example read Explorer screens when picking a video to watch. Works fine.
BRU sadly does not handle this AT ALL. The display overflows the side and bottom, and there are no scroll bars top or bottom to cater for this. Right clicking on the title bar offers no right click menu. So even I can use some of the options - replace, for example, and see that they work, the "Rename" button is out of sight and out of reach.
Not all apps handle this well, and one has to make adjustments, but most do, using the Browser for example, I will reduce the text size, which is easy to do.
I have tried using the Properties/Compatibility/DPI settings to no effect,
It would be a real bonus if you could fix this. Sadly I can't post an image, but I hope the above description suffices.
I should add, that when I also try on the Surface, it's the same - so it is not a result of the projection to a second screen.